静脉注射免疫球蛋白治疗韦格纳肉芽肿病。

Treatment of Wegener's granulomatosis with intravenous immunoglobulin.

作者信息

Richter C, Schnabel A, Csernok E, Reinhold-Keller E, Gross W L

机构信息

Dept. of Rheumatology, Medical University of Lübeck, Germany.

出版信息

Adv Exp Med Biol. 1993;336:487-9. doi: 10.1007/978-1-4757-9182-2_88.

DOI:10.1007/978-1-4757-9182-2_88

PMID:8296662

Abstract

We report about the treatment of eight patients with Wegener's granulomatosis and one patient with systemic pANCA-associated vasculitis with a single course of high-dose intravenous immunoglobulin (IVIG). In 5 of 9 patients (55%) this resulted in significant clinical improvement, in two patients a decrease of the ANCA-titre was seen.

摘要

我们报告了对8例韦格纳肉芽肿患者和1例系统性抗中性粒细胞胞浆抗体（ANCA）相关血管炎患者采用单疗程大剂量静脉注射免疫球蛋白（IVIG）进行治疗的情况。9例患者中有5例（55%）临床症状显著改善，2例患者的ANCA滴度下降。