Velimirovic D, Petrovic P, Djukic P, Ristic M, Pavlovic S U
Institute of Cardiovascular Diseases, University Clinical Center, Belgrade, Yugoslavia.
Eur J Cardiothorac Surg. 1993;7(11):580-6. doi: 10.1016/1010-7940(93)90243-5.
The aim of the study was to analyze the effect of surgical moderation of conduction from the atrium to the atrio-ventricular (AV) node on ventricular response in 30 patients with atrial fibrillation (AF) undergoing mitral valve replacement (MVR). Besides the usual diagnostics, echocardiographic evaluation of the size of the left atrium was performed in all patients, as a parameter of stability of rhythm conversion by drugs. Surgical treatment was applied exclusively in cases where, judging by these parameters, there was little chance for drug treatment to be effective. All patients (mean age 50 years) had severe mitral valve disease (NYHA III and IV), chronic AF and irregular ventricular rate, and underwent mitral valve replacement with mechanical valve. The patients were divided into three groups of ten patients each. In group I: MVR was combined with interatrial septal incision (IASI) to study the effect of the moderation of conduction from the interatrial septum to the AV node; in group II: after MVR, IASI was combined with crista terminalis myotomy (CTM) to study the additional effect of the moderation of conduction along the crista terminalis to the AV node; in group III (control): MVR was performed through left atriotomy, without antiarrhythmic incisions. Ventricular response was studied in two phases: In the immediate postoperative period (up to 7 days), using continuous electrocardiographic (ECG) monitoring, and 2 months postoperatively, using 24 h Holter monitoring with the results compared to a preoperative 24 h recording. Postoperative AF occurred in all patients.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是分析对30例接受二尖瓣置换术(MVR)的心房颤动(AF)患者进行从心房到房室(AV)结传导的手术调控对心室反应的影响。除常规诊断外,对所有患者均进行了左心房大小的超声心动图评估,作为药物节律转换稳定性的一个参数。仅在根据这些参数判断药物治疗效果不佳的情况下才进行手术治疗。所有患者(平均年龄50岁)均患有严重二尖瓣疾病(纽约心脏协会III级和IV级)、慢性AF且心室率不规则,并接受了机械瓣膜二尖瓣置换术。患者被分为三组,每组十例。在第一组中:MVR联合房间隔切开术(IASI),以研究从房间隔到AV结传导调控的效果;在第二组中:MVR后,IASI联合界嵴肌切开术(CTM),以研究沿界嵴到AV结传导调控的额外效果;在第三组(对照组)中:通过左心房切开术进行MVR,不做抗心律失常切口。在两个阶段研究心室反应:术后即刻(至7天),采用连续心电图(ECG)监测;术后2个月,采用24小时动态心电图监测,并将结果与术前24小时记录进行比较。所有患者术后均发生AF。(摘要截断于250字)