Ovulation induction with GnRH agonist and human menopausal gonadotropins: response in patients with one versus two ovaries.

OBJECTIVE

To examine the effect of oophorectomy on response to gonadotropin releasing hormone-agonist/human menopausal gonadotropin (GnRH-a/hMG) for in vitro fertilization (IVF).

DESIGN

Retrospective review.

SETTING

Tertiary care academic institution.

PATIENTS

Ninety-one infertile patients undergoing IVF. Eighty-four women had two ovaries and seven had only one ovary.

RESULTS

There was no difference observed between women with one versus two ovaries with regard to response to medications, hormone production, number of oocytes retrieved and fertilized, or the number of embryos cleaved and transferred.

CONCLUSION

Women with only one ovary are at no reproductive disadvantage when undergoing ovulation induction for IVF.