睾酮对草原田鼠（Microtus ochrogaster）父性行为及加压素免疫反应性投射的影响。

Testosterone effects on paternal behavior and vasopressin immunoreactive projections in prairie voles (Microtus ochrogaster).

作者信息

Wang Z, De Vries G J

机构信息

Department of Psychology, University of Massachusetts, Amherst 01003.

出版信息

Brain Res. 1993 Dec 17;631(1):156-60. doi: 10.1016/0006-8993(93)91203-5.

DOI:10.1016/0006-8993(93)91203-5

PMID:8298988

Abstract

Castration reduced paternal responsiveness of male prairie voles (Microtus ochrogaster). Castration also reduced the number of vasopressin immunoreactive (AVP-ir) cells in the bed nucleus of the stria terminalis (BST) and medial amygdaloid nucleus (MA), as well as the density of AVP-ir fibers in the lateral septum. Testosterone treatment of castrated voles prevented these changes. The similarities in the effects of the hormonal manipulations on paternal responsiveness and AVP immunoreactivity provide further support for the hypothesis that AVP-ir projections of the BST and MA are implicated in paternal behavior.

摘要

阉割降低了雄性草原田鼠（Microtus ochrogaster）的父性反应。阉割还减少了终纹床核（BST）和杏仁内侧核（MA）中加压素免疫反应性（AVP-ir）细胞的数量，以及外侧隔中AVP-ir纤维的密度。对阉割后的田鼠进行睾酮治疗可防止这些变化。激素操作对父性反应和AVP免疫反应性的影响相似，这为BST和MA的AVP-ir投射与父性行为有关这一假说提供了进一步的支持。