Chang S L, Healy G R, McCabe L, Shumaker J B, Schultz M G
Health Lab Sci. 1975 Jan;12(1):1-7.
The 161A strain of Naegleria isolated from a human nasal swab and reported earlier was further studied for its growth pattern, cyst-wall appearance, cytopathic effect on primary monkey kidney cells, and pathogenicity in mice. Results obtained in the study establish the pathogenic status of this strain. This constitutes the first isolation of a pathogenic Naegleria from a human nasal cavity.
先前报道的从人类鼻拭子中分离出的161A株耐格里属阿米巴原虫,进一步研究了其生长模式、囊壁外观、对原代猴肾细胞的细胞病变效应以及在小鼠中的致病性。该研究获得的结果确定了该菌株的致病状态。这是首次从人类鼻腔中分离出致病性耐格里属阿米巴原虫。