Phillips A O, Bewick M, Snowden S A, Hillis A N, Hendry B M
Renal Unit, Kings College Hospital (Dulwich), London, United Kingdom.
Clin Nephrol. 1993 Dec;40(6):352-4.
This paper assesses the impact of age on the outcome of cadaveric renal transplantation. Data are presented on 99 consecutive patients undergoing first renal allografts at one unit. Patients are divided into those aged less than 50 (n = 53), patients between 50 and 60 (n = 16), and those aged 60 years and over (n = 30). There was no significant difference in graft survival at one year between the three groups. There was however an increased mortality with increasing recipient age (1.9%, 12.5% and 20.0% respectively for each age group). The effect of increasing donor age on graft survival was also studied. Graft survival at two years for first grafts was not influenced by donor age. We conclude that age alone is not a criterion for exclusion of patients from transplant programs. In addition we provide data to support the use of elderly donors as a potential source of cadaveric renal grafts for certain patients.
本文评估年龄对尸体肾移植结果的影响。文中呈现了在一个单位连续接受首次肾移植的99例患者的数据。患者被分为年龄小于50岁的（n = 53）、50至60岁的（n = 16）以及60岁及以上的（n = 30）。三组患者术后一年的移植物存活率无显著差异。然而，随着受者年龄增加，死亡率上升（各年龄组分别为1.9%、12.5%和20.0%）。还研究了供者年龄增加对移植物存活的影响。首次移植术后两年的移植物存活不受供者年龄影响。我们得出结论，仅年龄不应作为将患者排除在移植项目之外的标准。此外，我们提供数据支持将老年供者作为某些患者尸体肾移植物的潜在来源。
