小鼠纤连蛋白编码基因启动子区域的序列
Sequence of the mouse fibronectin-encoding gene promoter region.
作者信息
Polly P, Nicholson R C
机构信息
Carcinogenesis Research Unit, School of Pathology, University of New South Wales, Sydney, Australia.
出版信息
Gene. 1993 Dec 31;137(2):353-4. doi: 10.1016/0378-1119(93)90036-3.
PMID:8299972
Abstract
The polymerase chain reaction (PCR) procedure has been utilised to clone, from mouse genomic DNA, a region of the fibronectin (FN)-encoding gene (FN) which includes the 5' flanking nucleotide (nt) sequences. The mouse promoter nt sequence shows high homology to the rat and human FN promoters, including consensus nt sequences for several DNA-binding transcription factors.
摘要
聚合酶链反应（PCR）程序已被用于从小鼠基因组DNA中克隆纤连蛋白（FN）编码基因（FN）的一个区域，该区域包括5'侧翼核苷酸（nt）序列。小鼠启动子nt序列与大鼠和人类FN启动子具有高度同源性，包括几个DNA结合转录因子的共有nt序列。
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