Blumenthal N M, Singiser R T
Department of Periodontics, University of Illinois Health Sciences Center, College of Dentistry, Chicago 60612.
Int J Periodontics Restorative Dent. 1993 Aug;13(4):360-71.
The periodontal fenestration model was used in four young mongrel dogs to evaluate the ability of vertical root surface grooving to enhance and direct cell outgrowth and subsequent formation of new attachment at 2- and 6-week healing intervals. In each dog, three fenestration wounds were made on each side of the mandible. On the control side, the roots were planed to dentin, a barrier membrane was sutured over the wound, and the flaps were replaced over the membrane. The experimental side received three vertical grooves followed by membrane placement and flap replacement. Histologic and histometric analyses were performed to determine the amount of new bone, cementum, and ankylosis and maturation of wound healing. Grooved wounds demonstrated greater cementum and bone formation, primarily in the early wounds, in addition to a more mature attachment at 6 weeks. Grooving the root surface may enhance initial cell adhesion and proliferation, thereby accelerating new attachment formation.
在四只年轻的杂种犬身上采用牙周开窗模型，以评估垂直根面开槽在2周和6周愈合期增强并引导细胞生长以及随后形成新附着的能力。在每只犬的下颌骨两侧各制造三个开窗创口。在对照侧，将牙根刨至牙本质，在创口上缝合屏障膜，然后将瓣复位覆盖在膜上。实验侧则在垂直开槽后进行膜放置和瓣复位。进行组织学和组织计量学分析，以确定新骨、牙骨质的量以及骨粘连情况和创口愈合的成熟度。开槽创口显示出更多的牙骨质和骨形成，主要在早期创口，此外在6周时附着更成熟。在根面开槽可能会增强初始细胞黏附和增殖，从而加速新附着的形成。
