Seshadri M S, Kanagasabapathy A S, Cherian A M, Nair A, Jesudason S R
Christion Medical College & Hospital, Vellore.
J Assoc Physicians India. 1993 May;41(5):266-8.
Primary hyperaldosteronism was detected in 1% of patients evaluated for secondary hypertension in a referral hospital in Southern India. The presence of hypokalemia with inappropriate kaliuresis (24 hr. urine K > 20mEq) was an important diagnostic clue. High resolution CT scans were found to be useful for localising the tumour. Preoperatively nifedipine and spironolactone were employed to correct hypertension and hypokalemia. The same drugs were also found to be excellent for long-term control of hypertension and hypokalemia in patients who had bilateral adrenal hyperplasia and aldosteronism.
在印度南部一家转诊医院对继发性高血压进行评估的患者中，1%被检测出原发性醛固酮增多症。伴有不适当钾尿症（24小时尿钾>20mEq）的低钾血症的存在是一个重要的诊断线索。高分辨率CT扫描被发现有助于肿瘤定位。术前使用硝苯地平和螺内酯来纠正高血压和低钾血症。对于患有双侧肾上腺增生和醛固酮增多症的患者，同样的药物在长期控制高血压和低钾血症方面也被发现效果极佳。
