Bowman M C, Cooke I D, Lenton E A
University Department of Obstetrics and Gynaecology, Jessop Hospital for Women, Sheffield, UK.
Hum Reprod. 1993 Oct;8(10):1654-6. doi: 10.1093/oxfordjournals.humrep.a137908.
A prospective study was performed to determine whether a relationship exists between infertility as a result of pelvic adhesions, and raised follicle stimulating hormone (FSH). A total of 66 patients, who had a diagnostic laparoscopy and dye performed as part of their infertility work-up, had an early cycle serum FSH drawn one to two cycles after this procedure. Patients were divided into two groups, one with pelvic adhesions as a result of surgery, infection or endometriosis, and a control group consisting of those with a normal pelvis at laparoscopy or with minimal/mild endometriosis without adhesions. In the adhesion group, a correlation was noted between American Fertility Society (AFS) adhesion score and basal FSH concentration, although all FSH values for this group were within the normal range. This study suggests a correlation between pelvic adhesions and ovarian compromise, but a larger study involving more severe cases of adhesions is required to determine whether this finding is of clinical importance.
进行了一项前瞻性研究,以确定盆腔粘连导致的不孕症与促卵泡激素(FSH)升高之间是否存在关联。共有66例患者在不孕症检查过程中接受了诊断性腹腔镜检查和输卵管造影,并在该检查后的一至两个周期抽取了早卵泡期血清FSH。患者被分为两组,一组因手术、感染或子宫内膜异位症导致盆腔粘连,另一组为腹腔镜检查时盆腔正常或有轻微/轻度子宫内膜异位症且无粘连的对照组。在粘连组中,虽然该组所有FSH值均在正常范围内,但美国生育协会(AFS)粘连评分与基础FSH浓度之间存在相关性。这项研究表明盆腔粘连与卵巢功能受损之间存在相关性,但需要进行一项涉及更严重粘连病例的更大规模研究,以确定这一发现是否具有临床意义。