Zalud I, Conway C, Schulman H, Trinca D
Department of Obstetrics and Gynecology, Winthrop University Hospital, Mineola, New York 11501.
J Ultrasound Med. 1993 Dec;12(12):737-41. doi: 10.7863/jum.1993.12.12.737.
The aim of our study was to assess the age and hormonal influence on endometrial and myometrial thickness and uterine blood flow in postmenopausal women. One hundred and nine healthy postmenopausal women were examined by transvaginal ultrasonography and color Doppler ultrasonography. Twenty women (18.4%) were under continuous HRT for at least 1 year. In all patients, full thickness of the endometrium and half thickness of the myometrium was measured. Pulsed Doppler waveforms were used to calculate the RI for the left and right uterine arteries. Endometrium thickness in the groups without HRT did not change as the years of postmenopause progressed. This was also true for myometrial thickness. The resistance to blood flow in the uterine arteries remained the same as the postmenopause progressed, but with each 5 year analysis, the ability to see the uterine arteries decreased. The duration of the therapy did not affect the measured parameters. The thickness of the endometrium was larger in the groups with HRT in comparison with all groups without HRT (P < 0.01). Myometrial thickness and uterine blood flow are not affected and did not show any significant influence from HRT. In conclusion, continuous HRT significantly influences the thickness of the postmenopausal endometrium but not of the myometrium or the uterine artery blood flow.
我们研究的目的是评估年龄和激素对绝经后女性子宫内膜、肌层厚度及子宫血流的影响。对109名健康绝经后女性进行经阴道超声检查和彩色多普勒超声检查。20名女性（18.4%）接受持续激素替代疗法（HRT）至少1年。测量所有患者的子宫内膜全层厚度和肌层半层厚度。使用脉冲多普勒波形计算左右子宫动脉的阻力指数（RI）。未接受HRT的组中，随着绝经年限的增加，子宫内膜厚度未发生变化。肌层厚度也是如此。随着绝经进程，子宫动脉血流阻力保持不变，但每5年分析一次，子宫动脉的显影能力下降。治疗持续时间不影响所测参数。与所有未接受HRT的组相比，接受HRT的组子宫内膜厚度更大（P<0.01）。肌层厚度和子宫血流不受HRT影响，未显示出任何显著影响。总之，持续HRT显著影响绝经后子宫内膜厚度，但不影响肌层厚度或子宫动脉血流。
