Matsumoto Y, Akama Y, Tase C, Okuaki A
Department of Anesthesiology, Fukushima Medical College.
Masui. 1993 Dec;42(12):1793-8.
The changes of the P50, 2,3-DPG and sodium as well as potassium of red blood cells in perioperative period were studied in 12 patients who underwent hemodilutional autotransfusion (HAT). P50 and 2, 3-DPG did not show remarkable changes before the third day after operation, but increased significantly on 5th and 7th day. There was a positive correlation between P50 and 2,3-DPG. Potassium of red blood cell increased significantly except on the first day. But sodium of red blood cell showed no remarkable change. In conclusion, our data demonstrate that the tissue oxygen supply from the red blood cell is maintained, because P50 did not decrease. Sodium in the red blood cell does not show remarkable changes, and therefore the membrane function of the red blood cell should be kept intact.
对12例行血液稀释自体输血（HAT）的患者围手术期红细胞的P50、2,3-二磷酸甘油酸（2,3-DPG）以及钠、钾变化进行了研究。P50和2,3-DPG在术后第三天前无明显变化，但在第5天和第7天显著升高。P50与2,3-DPG之间呈正相关。红细胞钾除第一天外显著升高。但红细胞钠无明显变化。总之，我们的数据表明，由于P50未降低，红细胞对组织的氧供应得以维持。红细胞内钠无明显变化，因此红细胞的膜功能应保持完整。
