Miyagawa H, Yamada R, Tamura S, Ishihara T
Department of Respiratory Medicine, NTT Tokyo Health Administration Center, Japan.
Kekkaku. 1993 Dec;68(12):739-44.
A study was made on the annual changes in the positive rate for acid-fast bacilli (AFB) at the initial bacteriological examination of newly detected pulmonary tuberculosis among male NTT (Nippon Telegraph and Telephone Corporation) employees in the Tokyo area during a period of 32 years from 1960 through 1991. The influence on the changes of recent introduction of fiberoptic bronchoscopy for obtaining the specimen was also analyzed, and the following results were obtained. 1. Results obtained by the conventional bacteriological method using expectorated sputum or aspirated gastric juice as the specimens. (1) The annual incidence of bacteriologically positive (smear and/or culture positive) cases constantly decreased and reached the lowest in 1981, then ceased to decline and remained at the level of 1981. (2) The annual ratio of AFB positive by smear and the ratio of smear and/or culture positive cases to the newly detected cases of pulmonary tuberculosis were constant during the entire observation period. (3) The ratio of AFB positive by smear to the newly detected cases annually increased but did not increase when the observation period was limited to within 1976 to 1991. 2. Results obtained by fiberoptic bronchoscopy in combination with conventional bacteriological methods. (1) Both the annual incidence of smear and/or culture positive cases and the ratio of these cases to the newly detected cases of pulmonary tuberculosis showed a tendency to increase in both the 80's and 90's.(ABSTRACT TRUNCATED AT 250 WORDS)
对1960年至1991年这32年间东京地区日本电报电话公司男性新确诊肺结核患者初次细菌学检查时抗酸杆菌(AFB)阳性率的年度变化进行了研究。还分析了近期引入纤维支气管镜获取标本对这些变化的影响,结果如下。1. 采用咳出痰液或吸出胃液作为标本的传统细菌学方法所获结果。(1)细菌学阳性(涂片和/或培养阳性)病例的年发病率持续下降,1981年降至最低,之后不再下降并维持在1981年的水平。(2)在整个观察期内,涂片AFB阳性的年比例以及涂片和/或培养阳性病例占新确诊肺结核病例的比例保持恒定。(3)涂片AFB阳性占新确诊病例的比例逐年上升,但当观察期限于1976年至1991年时则未上升。2. 纤维支气管镜检查结合传统细菌学方法所获结果。(1)涂片和/或培养阳性病例的年发病率以及这些病例占新确诊肺结核病例的比例在80年代和90年代均呈上升趋势。(摘要截于250词)