Thibault A, Figg W D, Cooper M R, Prindiville S A, Sartor A O, Headlee D J, Myers C E
Clinical Pharmacology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Pharmacotherapy. 1993 Nov-Dec;13(6):656-7.
Suramin, a drug used to treat parasitic diseases, is currently being investigated as a treatment for metastatic prostate cancer. A 73-year-old man had an anaphylactoid reaction following the first dose of suramin. It was treated successfully with epinephrine, diphenhydramine, and hydrocortisone. Investigators should be aware of the possibility of such a reaction with parenteral administration of this drug.
苏拉明是一种用于治疗寄生虫病的药物,目前正作为转移性前列腺癌的一种治疗方法进行研究。一名73岁男性在首次服用苏拉明后发生类过敏反应。该反应通过肾上腺素、苯海拉明和氢化可的松成功治疗。研究人员应意识到肠胃外给药这种药物时可能发生此类反应。