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Development of immortalized cells derived from 13DPC mouse limb buds as a system to study the effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) on limb bud cell differentiation.

作者信息

Rosen V, Capparella J, McQuaid D, Cox K, Thies R S, Song J, Wozney J

机构信息

Genetics Institute Inc., Cambridge, MA 02140.

出版信息

Prog Clin Biol Res. 1993;383A:305-15.

PMID:8302904
Abstract
摘要

相似文献

1
Development of immortalized cells derived from 13DPC mouse limb buds as a system to study the effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) on limb bud cell differentiation.源自13DPC小鼠肢芽的永生化细胞的开发,作为研究重组人骨形态发生蛋白-2(rhBMP-2)对肢芽细胞分化影响的系统。
Prog Clin Biol Res. 1993;383A:305-15.
2
Recombinant bone morphogenetic protein (BMP)-2 regulates costochondral growth plate chondrocytes and induces expression of BMP-2 and BMP-4 in a cell maturation-dependent manner.重组骨形态发生蛋白(BMP)-2调节肋软骨生长板软骨细胞,并以细胞成熟依赖的方式诱导BMP-2和BMP-4的表达。
J Orthop Res. 1997 May;15(3):371-80. doi: 10.1002/jor.1100150309.
3
Bone morphogenetic protein-2 (BMP-2) inhibits muscle development and promotes cartilage formation in chick limb bud cultures.骨形态发生蛋白-2(BMP-2)在鸡胚肢芽培养物中抑制肌肉发育并促进软骨形成。
Dev Biol. 1996 Mar 15;174(2):448-52. doi: 10.1006/dbio.1996.0087.
4
FGF-4 and BMP-2 have opposite effects on limb growth.成纤维细胞生长因子-4(FGF-4)和骨形态发生蛋白-2(BMP-2)对肢体生长具有相反的作用。
Nature. 1993 Jan 7;361(6407):68-71. doi: 10.1038/361068a0.
5
Dependence of mesenchymal cell responses on duration of exposure to bone morphogenetic protein-2 in vitro.体外间充质细胞反应对骨形态发生蛋白-2暴露持续时间的依赖性。
J Cell Physiol. 1997 Oct;173(1):93-101. doi: 10.1002/(SICI)1097-4652(199710)173:1<93::AID-JCP11>3.0.CO;2-O.
6
N- and E-cadherin mediate early human calvaria osteoblast differentiation promoted by bone morphogenetic protein-2.N-钙黏蛋白和E-钙黏蛋白介导骨形态发生蛋白-2促进的早期人类颅骨成骨细胞分化。
J Cell Physiol. 2000 Apr;183(1):117-28. doi: 10.1002/(SICI)1097-4652(200004)183:1<117::AID-JCP14>3.0.CO;2-#.
7
Fibroblast growth factor signaling regulates Dach1 expression during skeletal development.成纤维细胞生长因子信号传导在骨骼发育过程中调节Dach1的表达。
Dev Dyn. 2002 Sep;225(1):35-45. doi: 10.1002/dvdy.10132.
8
Bone morphogenetic protein-2 and transforming growth factor-beta2 interact to modulate human bone marrow stromal cell proliferation and differentiation.骨形态发生蛋白-2与转化生长因子-β2相互作用以调节人骨髓基质细胞的增殖和分化。
J Cell Biochem. 1998 Mar 15;68(4):411-26.
9
Bone morphogenetic protein-2 modulation of chondrogenic differentiation in vitro involves gap junction-mediated intercellular communication.骨形态发生蛋白-2对体外软骨形成分化的调节涉及缝隙连接介导的细胞间通讯。
J Cell Physiol. 2002 Nov;193(2):233-43. doi: 10.1002/jcp.10168.
10
Differential cell affinity and sorting of anterior and posterior cells during outgrowth of recombinant avian limb buds.重组禽肢芽生长过程中前后细胞的差异细胞亲和力及分选
Dev Biol. 2002 Oct 15;250(2):292-304.

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Genes with specificity for expression in the round cell layer of the growth plate are enriched in genomewide association study (GWAS) of human height.
在生长板的圆形细胞层中特异性表达的基因在人类身高的全基因组关联研究(GWAS)中富集。
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Reactivation of a developmental signaling center is required for therapeutic control of the murine periosteal niche.发育信号中心的重新激活对于治疗性控制小鼠骨膜龛具有重要意义。
Elife. 2019 Feb 8;8:e42386. doi: 10.7554/eLife.42386.
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Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2.经典Wnt信号传导对成骨细胞命运的特异性决定需要Bmp2。
Development. 2016 Dec 1;143(23):4352-4367. doi: 10.1242/dev.136879. Epub 2016 Oct 17.
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Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin.成骨细胞Smad4的产后消融通过与β-连环蛋白相互作用增强对经典Wnt信号的增殖反应。
J Cell Sci. 2013 Dec 15;126(Pt 24):5598-609. doi: 10.1242/jcs.132233. Epub 2013 Oct 7.
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delta-EF1 is a negative regulator of Ihh in the developing growth plate.delta-EF1 是发育中的生长板中 Ihh 的负调控因子。
J Cell Biol. 2009 Nov 30;187(5):685-99. doi: 10.1083/jcb.200904034. Epub 2009 Nov 23.
8
Treatment of resting zone chondrocytes with bone morphogenetic protein-2 induces maturation into a phenotype characteristic of growth zone chondrocytes by downregulating responsiveness to 24,25(OH)2D3 and upregulating responsiveness to 1,25-(OH)2D3.用骨形态发生蛋白-2处理静止区软骨细胞,通过下调对24,25(OH)2D3的反应性并上调对1,25-(OH)2D3的反应性,诱导其成熟为生长区软骨细胞的表型特征。
Endocrine. 1998 Dec;9(3):273-80. doi: 10.1385/ENDO:9:3:273.