Gastaut J L, Bartolomei F
Hôpital Sainte-Marguerite, Marseille.
Rev Neurol (Paris). 1993;149(6-7):416-8.
We report two cases of partial complex epilepsy associated with a lesion of the corpus callosum: a cavernoma in one case and a lesion of undetermined nature in the other. Similar cases have already been reported, notably with lipomas or agenesis of the corpus callosum, but they remain exceptional. Two mechanisms could explain such epilepsies: either the lesion extends to the cingulate gyrus whence the epileptic discharge may reach internal temporal structures (our case n. 1), or a temporal focus becomes autonomic after interruption of inhibitory callosal fibres (our case n. 2).
一例为海绵状血管瘤,另一例为性质未明的病变。类似病例此前已有报道,尤其是伴有脂肪瘤或胼胝体发育不全的情况,但仍属罕见。有两种机制可解释此类癫痫:要么病变延伸至扣带回,癫痫放电由此可能波及颞叶内部结构(我们的病例1),要么在胼胝体抑制性纤维中断后,颞叶病灶变得自主化(我们的病例2)。