Grahmann P R, Swoboda L, Bonnet R, Riede U N, Hasse J
Department of Thoracic Surgery, Albert-Ludwig University, Freiburg, Germany.
Thorac Cardiovasc Surg. 1993 Oct;41(5):312-7. doi: 10.1055/s-2007-1013879.
Therapy and course of pulmonary manifestations of carcinosarcomas in three patients are described. For this rare mixed tumor there is a prevalence among men between the ages of forty and seventy. Operative therapy should be employed whenever possible, because of the poor results achieved thus far using radiotherapy or chemotherapy. Carcinosarcomas were thought to have a worse prognosis than other non-small-cell bronchial carcinomas but an increasing number of reports indicate a similar clinical course and prognosis. Pneumonectomy was required for two of our patients and lobectomy was performed in the third. The period of observation extended over two years. One patient, tumor stage T4N0M0 died of his disease after seven months. The two other patients, tumor stages T3N0M0 and T2N1M0, were operated on thirty-three and thirty-five months ago respectively and are clinically disease-free and in good health.
描述了3例癌肉瘤肺表现的治疗及病程。对于这种罕见的混合性肿瘤，40至70岁男性中患病率较高。由于迄今为止放疗或化疗效果不佳，应尽可能采用手术治疗。癌肉瘤被认为比其他非小细胞支气管癌预后更差，但越来越多的报告表明其临床病程和预后相似。我们的2例患者需要进行肺切除术，第3例进行了肺叶切除术。观察期超过两年。1例肿瘤分期为T4N0M0的患者在7个月后死于该病。另外2例患者，肿瘤分期分别为T3N0M0和T2N1M0，分别于33个月和35个月前接受手术，目前临床无病且健康状况良好。
