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1980 - 1990年丹麦的宫颈机能不全与宫颈环扎术。一项基于登记处的流行病学调查。

Cervical incompetence and cerclage in Denmark 1980-1990. A register based epidemiological survey.

作者信息

Lidegaard O

机构信息

Department of Obstetrics and Gynecology, Hvidovre Hospital, University of Copenhagen, Denmark.

出版信息

Acta Obstet Gynecol Scand. 1994 Jan;73(1):35-8. doi: 10.3109/00016349409013390.

DOI:10.3109/00016349409013390
PMID:8304022
Abstract

OBJECTIVE

To assess the incidence rate of cervical incompetence diagnoses in Denmark 1980-1990 according to maternal age, to analyse regional variations, to investigate how often cerclage is applied, and finally to estimate abortion rates among women with cervical incompetence with and without cerclage.

DESIGN

A register-based retrospective cross section study.

SETTING

All Danish gynecological departments.

MATERIAL AND METHODS

Since 1977, all hospitalized patients in Denmark have been centrally recorded by diagnosis according to the ICD classification and by operation codes in The National Patient Register. From this database, all women with cervical incompetence (CI) and cerclage in the period 1980-1990 were identified. From the same database all cases of spontaneous abortions were registered.

RESULTS

A total of 2756 cases of cervical incompetence were registered in the period 1980-1990, corresponding to an incidence rate of 4.6/1000 births. The risk of cervical incompetence increased from 2/1000 births among women 15-19 years old to 7.5/1000 births among women 35-39 years old. The incidence rate of the CI-diagnosis fell 44% from 1980 to 1990. The incidence rates in different counties ranged from 1.7/1000 births to 10.0/1000 births. The average length of stay in hospital among patients with cervical incompetence was three weeks. Among patients with cervical incompetence, 61% were treated with cerclage. This per cent increased from 29% among women 15-19 years old to 68% among women 35-39 years old. 13.5% of women with CI experienced spontaneous abortion. This percentage increased from 12% for women 15-19 years old to 17% among women 40-44 years old (p < 0.01). Among women with CI and cerclage, the abortion rate was 17.6%.

CONCLUSION

In the period 1980-1990 the incidence rate of cervical incompetence in Denmark was on the average 4.6/1000 births. The incidence rate of the CI-diagnoses has fallen significantly during the last decade, and it increases four-fold with increasing age. Six out of ten patients with cervical incompetence were treated with cerclage.

摘要

目的

根据产妇年龄评估1980 - 1990年丹麦宫颈机能不全的诊断发病率,分析地区差异,调查宫颈环扎术的应用频率,最后估计有和没有接受宫颈环扎术的宫颈机能不全女性的流产率。

设计

基于登记处的回顾性横断面研究。

地点

丹麦所有妇科科室。

材料与方法

自1977年以来,丹麦所有住院患者均已按照国际疾病分类(ICD)的诊断和国家患者登记处的手术编码进行集中记录。从该数据库中,识别出1980 - 1990年期间所有患有宫颈机能不全(CI)并接受宫颈环扎术的女性。从同一数据库中登记了所有自然流产病例。

结果

1980 - 1990年期间共登记了2756例宫颈机能不全病例,发病率为4.6/1000例分娩。宫颈机能不全的风险从15 - 19岁女性的2/1000例分娩增加到35 - 39岁女性的7.5/1000例分娩。1980年至1990年,CI诊断的发病率下降了44%。不同县的发病率从1.7/1000例分娩到10.0/1000例分娩不等。宫颈机能不全患者的平均住院时间为三周。在宫颈机能不全患者中,61%接受了宫颈环扎术治疗。这一比例从15 - 19岁女性的29%增加到35 - 39岁女性的68%。13.5%的CI女性经历了自然流产。这一比例从15 - 19岁女性的12%增加到40 - 44岁女性的17%(p < 0.01)。在接受宫颈环扎术的CI女性中,流产率为17.6%。

结论

在1980 - 1990年期间,丹麦宫颈机能不全的发病率平均为4.6/1000例分娩。在过去十年中,CI诊断的发病率显著下降,并且随着年龄增长增加了四倍。十分之六的宫颈机能不全患者接受了宫颈环扎术治疗。

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