单卵双胞胎中的子宫内膜异位症。
Endometriosis in monozygotic twins.
作者信息
Moen M H
机构信息
Department of Obstetrics and Gynecology, National Hospital, University of Oslo, Norway.
出版信息
Acta Obstet Gynecol Scand. 1994 Jan;73(1):59-62. doi: 10.3109/00016349409013396.
OBJECTIVE
To study the reproductive and medical history of monozygotic twin sisters and mothers of patients with endometriosis.
MATERIAL AND METHODS
Among 515 patients with endometriosis, eight had a monozygotic twin sister all of whom had had a gynecological laparoscopy or laparotomy. In addition, five of their mothers had had a laparotomy. Details about these 13 relatives were obtained either from medical records (ten cases) or by unmistakable reports from the proband (three cases).
RESULT
Six of the monozygotic twin sisters (75%) also had symptomatic endometriosis compared with 3.8% among other types of sisters (p < 0.0005). Three of the mothers (38%) had either endometriosis or adenomyosis.
CONCLUSION
This study gives support to the assumption that endometriosis has a genetic trait.
目的
研究单卵双胞胎姐妹及子宫内膜异位症患者母亲的生育史和病史。
材料与方法
在515例子宫内膜异位症患者中，有8例患者有单卵双胞胎姐妹，她们均接受过妇科腹腔镜检查或剖腹手术。此外，她们的5位母亲接受过剖腹手术。这13位亲属的详细信息，10例来自病历，3例由先证者提供的确切报告获得。
结果
6例单卵双胞胎姐妹（75%）也患有症状性子宫内膜异位症，而其他类型姐妹的患病率为3.8%（p<0.0005）。3位母亲（38%）患有子宫内膜异位症或子宫腺肌病。
结论
本研究支持子宫内膜异位症具有遗传特征这一假设。
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