Evans P, Hofmann L
Family Practice Service, Reynolds Army Community Hospital, Fort Sill, Okla.
Am Fam Physician. 1994 Feb 1;49(2):427-31.
Malignant external otitis is an unusual but serious and potentially fatal condition that has only recently been described. It is an invasive pseudomonal infection of the external auditory canal and deep periauricular tissues that characteristically involves the bone and adjacent cartilaginous structures, and it may lead to osteomyelitis of the base of the skull. It typically occurs in elderly diabetic patients. Malignant external otitis can cause severe pain, necrosis of the external auditory canal and progressive palsies of the facial and cranial nerves. Treatment consists of debridement of external auditory canal granulation tissue and long-term therapy with an antipseudomonal cephalosporin or an antipseudomonal penicillin plus an aminoglycoside.
恶性外耳道炎是一种罕见但严重且可能致命的疾病，直到最近才被描述。它是外耳道和耳周深部组织的一种侵袭性假单胞菌感染，其特征是累及骨质及相邻软骨结构，可能导致颅骨骨髓炎。它通常发生在老年糖尿病患者中。恶性外耳道炎可引起严重疼痛、外耳道坏死以及面神经和颅神经进行性麻痹。治疗包括清除外耳道肉芽组织以及使用抗假单胞菌头孢菌素或抗假单胞菌青霉素加氨基糖苷类药物进行长期治疗。
