Plowman P N, Montefiore D S, Lightman S
Department of Radiotherapy, St Bartholomew's Hospital, London, UK.
Clin Oncol (R Coll Radiol). 1993;5(5):315-6. doi: 10.1016/s0936-6555(05)80909-4.
The eye has traditionally been regarded as a sanctuary site for drugs, but recent publications have shown evidence of penetration by drugs and subsequent clinical response of intraocular lymphomas. In this report, a chemotherapy regimen, including high dose methotrexate and cytosine arabinoside, was used to re-induce remission in a patient with intraocular lymphoma relapsing locally after prior radiotherapy. She remains disease free 18 months later.
传统上，眼睛一直被视为药物的庇护所，但最近的出版物显示了药物渗透以及眼内淋巴瘤后续临床反应的证据。在本报告中，一种包括高剂量甲氨蝶呤和阿糖胞苷的化疗方案被用于使一名先前接受放疗后局部复发的眼内淋巴瘤患者再次缓解。18个月后，她仍然无病。
