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继发于肝脏转移的低血糖症。一例病例报告及文献综述。

Hypoglycemia secondary to metastases to the liver. A case report and review of the literature.

作者信息

Younus S, Soterakis J, Sossi A J, Chawla S K, LoPresti P A

出版信息

Gastroenterology. 1977 Feb;72(2):334-7.

PMID:830586
Abstract

A 76-year-old man presented with hypoglycemic coma associated with metastatic liver disease. Serum immunoreactive insulin excluded insulinoma as a cause of hypoglycemia. Negative glucose responses to glucagon and epinephrine testing indicated failure of compensatory glycogenolysis. The patient's increased glucose requirements of 500 g per 24 hr were reduced to normal only after shrinkage of the liver tumor bulk was accomplished with chemotherapy. Hepatic hypoglycemia is discussed and the literature is reviewed.

摘要

一名76岁男性因转移性肝病出现低血糖昏迷。血清免疫反应性胰岛素排除了胰岛素瘤作为低血糖病因的可能。对胰高血糖素和肾上腺素试验的阴性血糖反应表明代偿性糖原分解功能衰竭。仅在通过化疗使肝脏肿瘤体积缩小后,患者每天500克的葡萄糖需求量增加才恢复正常。本文讨论了肝性低血糖并对相关文献进行了综述。

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