Christiansen C, Thomsen C, Rasmussen O, Balle M, Hauerslev C, Hansen C, Hermansen K
Institute of Clinical Experimental Research, Aarhus University, Denmark.
Diabet Med. 1993 Dec;10(10):958-61. doi: 10.1111/j.1464-5491.1993.tb00012.x.
To ensure an acceptable quality of life for Type 2 diabetic patients, the food recommendations have to be as liberal and individualized as possible. Unfortunately, disagreements exists about the consumption of different types of wine. Diabetic patients are advised by some to restrain their wine intake and to use dry wine containing little carbohydrate, while others are more liberal. The purpose of this study was to evaluate the effects of dry and sweet wine on the glycaemic control in Type 2 diabetes. Twelve diabetic patients consumed a light meal with either 300 ml tap water 300 ml dry white wine, 300 ml sweet white wine with ethanol added or 300 ml dry white wine with glucose added. Similar glucose, insulin, and triglyceride responses were obtained in all four situations. There was a greater suppression of the free fatty acid levels in the three situations with wine as compared with water (p < 0.001). This effect may be caused by an attenuation of the free fatty acid mobilization and esterification of free fatty acids to triglycerides induced by alcohol. Our results indicate that patients with well-controlled Type 2 diabetes can drink moderate amounts of wine with meals without risking acute deterioration of glycaemic control. Whether the wine is dry or sweet has no impact on the glycaemic control.
为确保2型糖尿病患者能有可接受的生活质量,食物推荐必须尽可能宽松且个性化。遗憾的是,对于不同类型葡萄酒的饮用存在分歧。一些人建议糖尿病患者限制葡萄酒摄入量并饮用含碳水化合物少的干型葡萄酒,而另一些人的态度则更为宽松。本研究的目的是评估干型葡萄酒和甜型葡萄酒对2型糖尿病患者血糖控制的影响。12名糖尿病患者食用清淡餐食,并分别饮用300毫升自来水、300毫升干白葡萄酒、300毫升添加了乙醇的甜白葡萄酒或300毫升添加了葡萄糖的干白葡萄酒。在所有四种情况下均获得了相似的血糖、胰岛素和甘油三酯反应。与饮用自来水相比,饮用葡萄酒的三种情况下游离脂肪酸水平的抑制作用更强(p < 0.001)。这种作用可能是由于酒精诱导的游离脂肪酸动员减弱以及游离脂肪酸酯化为甘油三酯所致。我们的结果表明,血糖控制良好的2型糖尿病患者用餐时饮用适量葡萄酒不会有血糖控制急性恶化的风险。葡萄酒是干型还是甜型对血糖控制没有影响。