Matveeva N P, Kaplan M A, Sloventantor V Iu, Bozadzhiev L L
Gematol Transfuziol. 1993 Jul-Aug;38(7):33-5.
Before and after treatment iron metabolism was evaluated in 37 iron deficient women given intravenous Ferrum Lek. In addition to standard blood counts and serum iron tests, iron metabolism was investigated with Fe-59 whole body radiometry in a low-background camera. The treatment effect was assessed in 1.3 and 6 months. The red blood cells and iron content in the serum returned to normal values. The effect persisted for 6 months. The initial 3 months iron accumulated in the depot, being further distributed in the blood. Total body iron 6 months after the treatment was at the baseline levels. It is thought adequate to use Ferrum Lek in the management of women with iron deficiency anemia.
对37名接受静脉注射Ferrum Lek的缺铁性女性患者在治疗前后进行了铁代谢评估。除了标准血常规和血清铁检测外,还使用低本底相机通过Fe-59全身辐射测量法研究铁代谢。在1.3个月和6个月时评估治疗效果。红细胞和血清铁含量恢复到正常水平。效果持续了6个月。最初3个月铁在储存库中蓄积,随后进一步分布到血液中。治疗6个月后全身铁含量处于基线水平。认为使用Ferrum Lek治疗缺铁性贫血女性是合适的。