糖尿病患者中微量白蛋白尿的患病率。

Prevalence of microalbuminuria in diabetic subjects.

作者信息

Sheth J, Trivedi B, Shah L, Sheth V S

机构信息

Sheth VS Hospital, Ahmedabad.

出版信息

J Assoc Physicians India. 1993 Sep;41(9):562-4.

PMID:8307909

Abstract

Total 193 diabetic patients were investigated to assess the prevalence of microalbuminuria. Urinary albumin excretion rate (UAER) was measured by radioimmunoassay (RIA) on 3 hours urine samples. The prevalence of microalbuminuria (UAER) > 15 micrograms/min was 41%. Microalbuminuria was commonly observed in patients having diabetes for more than 5 years. A significant correlation was found between duration of diabetes and microalbuminuria (p < 0.01). Glycemic control (fasting and postprandial blood sugar) did not show any correlation with UAER, whereas blood urea (r.39, p < 0.01), creatinine (r.26, p < 0.05) and chloride (r.24, p < 0.05) were positively correlated. A significant correlation was found between raised blood pressure and UAER (p < 0.01).

摘要

共对193例糖尿病患者进行了调查，以评估微量白蛋白尿的患病率。通过放射免疫分析法（RIA）对3小时尿液样本测定尿白蛋白排泄率（UAER）。微量白蛋白尿（UAER）>15微克/分钟的患病率为41%。微量白蛋白尿常见于患糖尿病超过5年的患者。发现糖尿病病程与微量白蛋白尿之间存在显著相关性（p<0.01）。血糖控制（空腹和餐后血糖）与UAER未显示任何相关性，而血尿素（r = 0.39，p<0.01）、肌酐（r = 0.26，p<0.05）和氯（r = 0.24，p<0.05）呈正相关。发现血压升高与UAER之间存在显著相关性（p<0.01）。