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[开放二尖瓣交界切开术治疗二尖瓣狭窄的临床再评估:与经皮经静脉二尖瓣交界切开术的对比研究]

[Clinical reassessment of open mitral commissurotomy as a treatment for mitral valve stenosis: a comparative study with percutaneous transvenous mitral commissurotomy].

作者信息

Takazawa A

机构信息

Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College.

出版信息

Nihon Kyobu Geka Gakkai Zasshi. 1994 Jan;42(1):38-45.

PMID:8308381
Abstract

Recently, percutaneous transvenous mitral commissurotomy (PTMC) was applied as a treatment for mitral valve stenosis (MS) and patients who received PTMC are increasing. The objective of this study is to establish therapeutic strategy for MS by comparing the indication and clinical results of open mitral commissurotomy (OMC: n = 95) and PTMC (n = 54). Both groups showed almost equivalent preoperative data in echocardiographic score and cardiac catheterization, and postoperatively, they obtained almost same results. But when the author defined that successful commissurotomy is to gain the following postoperative cardiac catheterization data: mitral valve gradient < 10 mmHg, mitral valve area (MVA) > or = 1.3 cm2, mitral regurgitation < or = Sellers II/IV, success rate was higher in OMC group up (72%) than PTMC group (63%). There was no difference between OMC group and PTMC group in the early mortality and late survival. But reoperation free rate at the four postoperative year was higher in OMC group (100%) than PTMC group (94.5%). We found that the factors of unsuccessful PTMC were 1) MVA < 0.8 cm2, 2) total echo score > or = 8 and 3) subvalvar thickening score > or = 3 in the preoperative data. We conclude that PTMC can be applied for MS with mild subvalvar lesion (subvalvar thickening score < or = 2) and OMC is superior to PTMC for releasing subvalvar stenosis than PTMC. However, mitral valve replacement might be a procedure of choice for MS with severe subvalvar lesion (subvalvar thickening score 4).

摘要

最近,经皮经静脉二尖瓣交界切开术(PTMC)被应用于二尖瓣狭窄(MS)的治疗,接受PTMC的患者数量正在增加。本研究的目的是通过比较直视二尖瓣交界切开术(OMC:n = 95)和PTMC(n = 54)的适应症和临床结果,建立MS的治疗策略。两组在超声心动图评分和心导管检查方面术前数据几乎相当,术后也获得了几乎相同的结果。但是,当作者将成功的交界切开术定义为术后心导管检查获得以下数据时:二尖瓣压差<10 mmHg,二尖瓣面积(MVA)>或= 1.3 cm²,二尖瓣反流<或= Sellers II/IV,OMC组的成功率(72%)高于PTMC组(63%)。OMC组和PTMC组在早期死亡率和晚期生存率方面没有差异。但术后四年的无再次手术率OMC组(100%)高于PTMC组(94.5%)。我们发现PTMC失败的因素为术前数据中1)MVA<0.8 cm²,2)总回声评分>或= 8以及3)瓣下增厚评分>或= 3。我们得出结论,PTMC可用于瓣下病变较轻(瓣下增厚评分<或= 2)的MS,在解除瓣下狭窄方面OMC优于PTMC。然而对于瓣下病变严重(瓣下增厚评分4)的MS,二尖瓣置换术可能是首选术式。

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