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Changes concurrent with initiation of abstinence from cocaine abuse.

作者信息

Avants S K, Margolin A, Kosten T R, Singer J L

机构信息

Department of Psychiatry, Yale University, New Haven, Connecticut.

出版信息

J Subst Abuse Treat. 1993 Nov-Dec;10(6):577-83. doi: 10.1016/0740-5472(93)90062-7.

DOI:10.1016/0740-5472(93)90062-7
PMID:8308943
Abstract

In an exploration of changes that occur with initiation of cocaine abstinence, this study examined treatment outcomes in four domains--behavior (cocaine use), affect (depression), cognition (schematic self-representations), and psychophysiology (reactivity to drug cues). Nineteen patients initially entered this 8-week outpatient psychopharmacotherapy trial for the treatment of cocaine dependence. Thirteen completed treatment, and eleven maintained abstinence during the last four weeks of the study. In addition to a demonstrated change in their cocaine-using behavior, these "abstainers" reported reduced depression, increased congruency with "ideal" self-schemas, increased discrepancy with "addict" self-schemas, and generally more positive self-representations. In addition, "abstainers" reported reduced posttreatment craving in the presence of cocaine cues, but evidenced no change in physiological reactivity. Implications of these findings for research and treatment are discussed.

摘要

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