Nishimura T, Sugita K, Aoki S, Takagi M
Department of Pediatrics, Osaka Medical College.
Jpn J Antibiot. 1993 Nov;46(11):1035-9.
Nine pediatric patients with bacterial infections (5 cases of tonsillitis, 3 cases of impetigo and 1 case of UTI) were treated with S-1108, and the efficacy and the safety were evaluated. The clinical responses to S-1108 treatment were excellent in 7 cases and good in 2. The efficacy rate was 100%. Bacteriologically, the causative organisms (Streptococcus pyogenes, Staphylococcus aureus, Haemophilus parainfluenzae and Escherichia coli) were eradicated. No clinical side effects were observed. Elevation of CK in 2 cases and eosinophilia in 1 case were noted.
9例细菌感染的儿科患者（5例扁桃体炎、3例脓疱病和1例尿路感染）接受了S - 1108治疗，并对其疗效和安全性进行了评估。S - 1108治疗的临床反应7例为优，2例为良。有效率为100%。细菌学上，致病微生物（化脓性链球菌、金黄色葡萄球菌、副流感嗜血杆菌和大肠杆菌）被根除。未观察到临床副作用。注意到2例肌酸激酶升高和1例嗜酸性粒细胞增多。
