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[肺及下呼吸道原发性恶性黑色素瘤]

[Primary malignant melanoma of the lung and lower respiratory tract].

作者信息

Barzó P, Tuka P, Minik K, Kiss J I

机构信息

Szent Ferenc Kórház Miskolc, III. Tüdöbelgyógyászat.

出版信息

Orv Hetil. 1994 Jan 30;135(5):245-9.

PMID:8309681
Abstract

After detailed analysis of the international special literature, the authors found--together with their own two patients--only 18 cases, considered primer malignant melanoma of the lower respiratory tract and/or lung. Of the accepted criteria, they dispute the obduction's absolute evidentiary role, because among primer patients there are the most who survives, even a decade. In seven cases tumour was located endobronchially and in one patient in the trachea. It was manifested endobronchially and on the dependent lung-areas, simultaneously in two patients and merely parenchymally, in eight. There was a successful resection in fourteen of 18 cases. Survival was influenced primarily by the operability depending on distension of the tumour. Besides procedures forming opinions, bronchoscopy and histological examinations of bioptatum gained this way play a greater role than usual in determining the tumour's primarity, localisation, operability and type of surgery, respectively. Namely, only operated patients can rely on a long survival.

摘要

在对国际专业文献进行详细分析后,作者们连同他们自己的两名患者,仅发现18例被认为是下呼吸道和/或肺部原发性恶性黑色素瘤的病例。在公认的标准中,他们对尸检的绝对证据作用提出质疑,因为在原发性患者中,存活时间最长的甚至可达十年。7例肿瘤位于支气管内,1例位于气管。肿瘤在支气管内和肺下垂部位同时出现的有2例,仅在肺实质出现的有8例。18例中有14例成功切除。生存主要受肿瘤扩张程度影响的可切除性影响。除了形成诊断意见的程序外,通过这种方式获得的支气管镜检查和活检组织的组织学检查在确定肿瘤的原发性、定位、可切除性和手术类型方面比通常发挥更大的作用。也就是说,只有接受手术的患者才能有较长的生存期。

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