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MR imaging of deferoxamine-induced bone dysplasia in an 8-year-old female with thalassemia major.

作者信息

Miller T T, Caldwell G, Kaye J J, Arkin S, Burke S, Brill P W

机构信息

Department of Radiology and Nuclear Medicine, Hospital for Special Surgery, New York, NY.

出版信息

Pediatr Radiol. 1993;23(7):523-4. doi: 10.1007/BF02012138.

DOI:10.1007/BF02012138
PMID:8309753
Abstract

Bone changes in thalassemic patients receiving deferoxamine therapy for iron chelation include metaphyseal and growth plate irregularities. We present a case of an 8-year-old female with thalassemia major, who had magnetic resonance imaging after plain radiographs had shown metaphyseal changes in the distal femur. The signal characteristics of these abnormalities were consistent with hyaline cartilage; the surrounding marrow showed no evidence of iron overload.

摘要

相似文献

1
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2
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引用本文的文献

1
Deferoxamine-induced dysplasia-like skeletal abnormalities at radiography and MRI.铁胺诱导的骨骼发育不良样影像学异常。
Pediatr Radiol. 2013 Sep;43(9):1159-65. doi: 10.1007/s00247-013-2645-x. Epub 2013 Apr 6.
2
MRI marrow observations in thalassemia: the effects of the primary disease, transfusional therapy, and chelation.
Pediatr Radiol. 1995;25(8):607-13. doi: 10.1007/BF02011827.

本文引用的文献

1
Deferoxamine-induced growth retardation in patients with thalassemia major.去铁胺导致重型地中海贫血患者生长发育迟缓。
J Pediatr. 1988 Oct;113(4):661-9. doi: 10.1016/s0022-3476(88)80375-5.
2
Deferoxamine-induced bone dysplasia in patients with thalassemia major.去铁胺诱发的重型地中海贫血患者骨发育异常
AJR Am J Roentgenol. 1991 Mar;156(3):561-5. doi: 10.2214/ajr.156.3.1899759.
3
Growth failure and bony changes induced by deferoxamine.去铁胺所致生长发育迟缓及骨骼改变
Am J Pediatr Hematol Oncol. 1992 Spring;14(1):48-56. doi: 10.1097/00043426-199221000-00007.
4
Growth plate of the normal knee: evaluation with MR imaging.正常膝关节生长板：磁共振成像评估
Radiology. 1992 Apr;183(1):119-23. doi: 10.1148/radiology.183.1.1549657.
5
Growth plate injury of the long bones in treated beta-thalassemia.经治疗的β地中海贫血患者长骨生长板损伤
Skeletal Radiol. 1992;21(1):39-44. doi: 10.1007/BF00243093.