Kottke B A
Watson Clinic, Lakeland, Florida.
Postgrad Med. 1994 Feb 1;95(2):51-3, 57-8, 63-5.
Plasma contains four major lipoprotein particles: chylomicrons, VLDLs, LDLs, and HDLs. How cholesterol is metabolized depends on the particle with which it is associated. Thus, treatment for hypercholesterolemia is most effective when it is designed to fit the lipoprotein features of a given patient. Dr Kottke describes the five common forms of hyperlipoproteinemia and provides specific therapeutic approaches for each.
乳糜微粒、极低密度脂蛋白(VLDL)、低密度脂蛋白(LDL)和高密度脂蛋白(HDL)。胆固醇的代谢方式取决于与之相关的颗粒。因此,针对高胆固醇血症的治疗,若能根据特定患者的脂蛋白特征进行设计,效果最为显著。科特克博士描述了高脂蛋白血症的五种常见形式,并针对每种形式提供了具体的治疗方法。