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实验室应激对非胰岛素依赖型糖尿病患者血糖的急性影响。

Acute effects of laboratory stress on blood glucose in noninsulin-dependent diabetes.

作者信息

Goetsch V L, VanDorsten B, Pbert L A, Ullrich I H, Yeater R A

机构信息

Department of Psychology, West Virginia University, Morgantown 26506.

出版信息

Psychosom Med. 1993 Nov-Dec;55(6):492-6. doi: 10.1097/00006842-199311000-00004.

DOI:10.1097/00006842-199311000-00004
PMID:8310109
Abstract

The acute effects of two psychological stressors (personally stressful imagery and threat of shock) on blood glucose (BG), heart rate, blood pressure, skin conductance, and subjective stress were studied in 22 noninsulin-dependent diabetic adults and nine healthy, nondiabetic subjects similar in age, weight, education and sex. The diabetic group's BG rose significantly after threat of shock (M change from rest = 18.4 mg/dL, p < .05), although the nondiabetic group's BG remained stable throughout the assessment. Significant increases in subjective stress ratings (p < .05) and skin conductance level (p < .05) paralleled the noninsulin-dependent diabetes mellitis (NIDDM) subjects' BG response to threat of shock. The findings suggest that some stressors can have hyperglycemic effects on individuals with NIDDM, although generalization of these findings to the natural environment remains to be demonstrated. The methodology used is contrasted with other studies that have failed to demonstrate stress effects on BG.

摘要

在22名非胰岛素依赖型糖尿病成年人和9名年龄、体重、教育程度及性别相近的健康非糖尿病受试者中,研究了两种心理应激源(个人压力意象和电击威胁)对血糖(BG)、心率、血压、皮肤电导率和主观压力的急性影响。糖尿病组在受到电击威胁后血糖显著升高(与静息时相比平均变化为18.4mg/dL,p<.05),而在整个评估过程中,非糖尿病组的血糖保持稳定。主观压力评分(p<.05)和皮肤电导率水平(p<.05)的显著增加与非胰岛素依赖型糖尿病(NIDDM)受试者对电击威胁的血糖反应平行。研究结果表明,某些应激源可能对NIDDM个体产生高血糖效应,尽管这些发现能否推广到自然环境仍有待证明。所采用的方法与其他未能证明应激对血糖有影响的研究形成对比。

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