Thomas J H
Department of Genetics, University of Washington, Seattle 98195.
Trends Genet. 1993 Nov;9(11):395-9. doi: 10.1016/0168-9525(93)90140-d.
Partial functional redundancy among genes is frequently observed in a wide range of organisms and processes, but the selective value of such redundancy is not immediately apparent. Any fully redundant function should be evolutionarily unstable: unless selection acts to maintain the redundancy it will tend to be lost by mutational drift. I discuss four possible mechanisms by which selection might act to maintain genetic redundancy.
基因间的部分功能冗余在广泛的生物体和过程中经常被观察到,但其冗余的选择价值并不直接明显。任何完全冗余的功能在进化上都应该是不稳定的:除非选择作用来维持这种冗余,否则它往往会因突变漂变而丢失。我讨论了选择可能用来维持基因冗余的四种可能机制。