[The characteristics of calculus formation in the kidneys of patients in families predisposed to urolithiasis].

To specify the implication of the genetic factors in formal genesis of urolithiasis, the pattern of stone formation was investigated in 206 probands with urolithiasis hereditary loading versus 324 patients rejecting family history of this disease. Distribution of the disease forms was considered in correlation with mineral metabolism derangement and hereditary loading in the proband. It was found that severe urolithiasis occurs more frequently in the groups with phosphorus-calcium urolithiasis. These groups also included many families with the disease history. Numerous cases of urolithiasis of hyperparathyroidism etiology suggest endocrine disorders involvement in urolithiasis onset. Clarification of hereditary loading and its distribution in the families of urolithiasis patients allows a purposeful control of the families members to render them prophylactic aid.