车间单克隆抗体与正常和病理绵羊淋巴结的反应性。

Reactivity of workshop monoclonal antibodies with normal and pathological ovine lymph nodes.

作者信息

Pépin M, Bernard S, Menanteau P, Olivier M, Berthon P, Lantier F

机构信息

Laboratoire de Pathologie Infectieuse et Immunologie, INRA-Centre de Recherches de Tours, Nouzilly, France.

出版信息

Vet Immunol Immunopathol. 1993 Nov;39(1-3):249-67. doi: 10.1016/0165-2427(93)90187-9.

DOI:10.1016/0165-2427(93)90187-9

PMID:8310649

Abstract

The monoclonal antibodies (82 mAbs) included in the Second Workshop that belonged to agreed named bovine CD and workshop clusters were tested for their reactivity and tissue distribution on (1) normal sheep lymph nodes and (2) pathological sheep lymph nodes. Pathological lymph nodes were induced following experimental infection with Corynebacterium pseudotuberculosis and were characterized by the presence of typical pyogranulomas. Amongst the 82 mAbs tested, 38 reacted with sheep lymph nodes. The results of these tests are presented and discussed.

摘要

第二届研讨会上包含的属于已商定命名的牛CD和研讨会集群的单克隆抗体（82种单克隆抗体），针对其在（1）正常绵羊淋巴结和（2）病理性绵羊淋巴结上的反应性和组织分布进行了检测。病理性淋巴结是在实验性感染假结核棒状杆菌后诱导产生的，其特征是存在典型的脓性肉芽肿。在测试的82种单克隆抗体中，有38种与绵羊淋巴结发生反应。展示并讨论了这些测试的结果。