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[硬膜外麻醉与截瘫产妇自主神经反射亢进的预防]

[Epidural anesthesia and prevention of autonomic hyperreflexia in a paraplegic parturient].

作者信息

Kaidomar M, Raucoules M, Ben Miled M, Carlon M, Grimaud D

机构信息

Département d'Anesthésie-Réanimation, Hôpital Saint-Roch, Nice.

出版信息

Ann Fr Anesth Reanim. 1993;12(5):493-6. doi: 10.1016/s0750-7658(05)80997-9.

Abstract

Pregnancy in a patient suffering from high spinal cord lesions is unusual and can lead to serious autonomic hyperreflexia during delivery. Epidural anaesthesia has been suggested as a means of decreasing such a risk. This clinical report presents the case of a paraplegic patient with lesions above the T3 level who had spinal anaesthesia for a Caesarean section. Her first delivery, six years earlier and without spinal anaesthesia was complicated by serious autonomic hyperreflexia with severe hypertension, seizures and inhalation. These symptoms were at first interpreted as eclampsia. For the Caesarean section, spinal anaesthesia using 0.25% bupivacaine in divided doses presented no difficulty, in spite of important lordosis, and permitted the delivery of a newborn with an Apgar score of 10 at one minute. The upper sympathetic level reached (T4-T6) was assessed by the discontinuing of muscular spasticity and contractures elicited by cutaneous stimuli. At the present time, spinal anaesthesia is the best method for preventing autonomic hyperreflexia. General anaesthesia, especially with halothane, is effective, but requires a deeper anaesthesia with the risk of serious hypotension and its possible repercussions on the fetus. Moreover it does not decrease the risk of autonomic hyperreflexia during the postoperative period.

摘要

患有高位脊髓损伤的患者怀孕并不常见,且在分娩期间可能导致严重的自主神经反射亢进。硬膜外麻醉被认为是降低此类风险的一种方法。本临床报告介绍了一名截瘫患者的病例,该患者T3水平以上有损伤,因剖宫产接受了脊髓麻醉。她六年前的首次分娩未进行脊髓麻醉,并发严重的自主神经反射亢进,伴有严重高血压、癫痫发作和吸入症状。这些症状起初被误诊为子痫。对于此次剖宫产,尽管有明显的脊柱前凸,但分剂量使用0.25%布比卡因进行脊髓麻醉并无困难,且顺利分娩出一名1分钟时阿氏评分10分的新生儿。通过停止皮肤刺激引起的肌肉痉挛和挛缩来评估达到的上交感神经水平(T4 - T6)。目前,脊髓麻醉是预防自主神经反射亢进的最佳方法。全身麻醉,尤其是使用氟烷,是有效的,但需要更深的麻醉深度,存在严重低血压的风险及其对胎儿可能产生的影响。此外,它并不能降低术后自主神经反射亢进的风险。

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