Ribet M
Clinique Chirurgicale Ouest, CHU, Lille.
Ann Chir. 1993;47(8):766-8.
Nineteen lympho-epithelial thymomas initially considered to be unresectable were treated by irradiation. Secondary resection was complete in 10 cases and incomplete in 98 cases. Total resection is still the best treatment for lympho-epithelial thymoma. Adjuvant therapy improves its results when resection is not complete. When resection appears to be impossible to perform, pre-operative irradiation can facilitate tumour excision. If the post-irradiation resection is complete, its result is as good as after total primary excision. If it is incomplete, its result is comparable with the result of radio/chemotherapy and inferior to the result of incomplete primary excision with post-operative adjuvant therapy. It remains difficult to appreciate the benefit of neo-adjuvant radiotherapy.
19例最初被认为无法切除的淋巴上皮型胸腺瘤接受了放疗。二次切除在10例中完整,在9例中不完整。完整切除仍是淋巴上皮型胸腺瘤的最佳治疗方法。当切除不完整时,辅助治疗可改善其效果。当似乎无法进行切除时,术前放疗可促进肿瘤切除。如果放疗后切除完整,其效果与初次完全切除后相同。如果不完整,其效果与放化疗的效果相当,且不如初次不完全切除后行术后辅助治疗的效果。新辅助放疗的益处仍难以评估。