Barretto A C, Arteaga E, Mady C, Ianni B M, Bellotti G, Pileggi F
Instituto do Coração, Hospital das Clínicas, FMUSP.
Arq Bras Cardiol. 1993 Apr;60(4):225-7.
To verify if the ventricular function and the incidence of arrhythmias in patients of both sexes could be predominant in male patients with Chagas' disease.
Six hundred and thirty one patients were studied, 329 female and 302 male, with age of 10 to 64 years old (mean 40). All patients were submitted to M mode echocardiographic study to analyse the ejection fraction (EF). To verify the importance of the ventricular dysfunction in male and female patients, they were divided according to the EF in three groups: A) normal EF, B) EF between 0.64 and 0.45 and C) EF less than 0.44. The incidence of ventricular tachycardia was analyzed at the stress test or 24h Holter studies.
The number of patients with depressed EF was more frequent on male patients (p < 0.0001). The incidence of ventricular tachycardia was similar in both sexes, however it was more frequent in patients with ventricular dysfunction.
Our results show that there are greater myocardial dysfunction on male patients, what could explain the worse prognosis observed on patients of this sex.
验证在恰加斯病患者中，两性患者的心室功能和心律失常发生率在男性患者中是否更为突出。
对631例患者进行了研究，其中女性329例，男性302例，年龄在10至64岁之间（平均40岁）。所有患者均接受M型超声心动图检查以分析射血分数（EF）。为了验证心室功能障碍在男性和女性患者中的重要性，根据EF将他们分为三组：A）EF正常，B）EF在0.64至0.45之间，C）EF小于0.44。在压力测试或24小时动态心电图研究中分析室性心动过速的发生率。
EF降低的患者数量在男性患者中更为常见（p < 0.0001）。两性室性心动过速的发生率相似，然而在心室功能障碍患者中更为常见。
我们的结果表明，男性患者存在更严重的心肌功能障碍，这可以解释该性别患者观察到的更差预后。
