Pomerantzeff P M, Brandão C M, Amato M, Fukushima J, Horta P, Ratti M, Medeiros C C, Tarasoutichi F, Cardoso L F, Grinberg M
Instituto do Coração do Hospital das Clínicas-FMUSP, São Paulo.
Arq Bras Cardiol. 1993 May;60(5):321-5.
To demonstrate the importance of the preservation of mitral annulus-chordae tendineae-papillary muscles continuity in mitral valve replacement.
We studied 21 patients who were submitted to mitral valve replacement, divided in two randomized groups: group 1, 12 cases who undergone mitral valve replacement, with preservation of the posterior leaflet and correspondent chordae tendineae; and group 2-9 cases who undergone conventional mitral valve replacement, excising the mitral valve apparatus. The left ventricular function was studied both, in the pre and post operative period, by echocardiography, cardiac catheterization, and radioisotopic study. The statistical analysis was done by the Wilcoxson's test.
There were no early post operative deaths. Analyzing the results of the ejection fraction by the radioisotopic study we found a significant difference (p = 0.03) between the percentual decrease of the two groups. The results of the fractional shortening were higher in group 1 than in group 2, however not significant. The left ventricular diastolic diameters average was lower in group 1 than in group 2, so as the left atrium diameter. We found a decrease in left ventricular end-diastolic pressure in group 1, however there was an increase in group 2, by the cardiac catheterization. There was a proportional increase in group 1 both in lung artery and lung capillary pressures. There was a significant difference (p = 0.05) between the average values of right ventricular diastolic pressure.
There is better preservation of left ventricular function in group 1.
论证在二尖瓣置换术中保留二尖瓣环-腱索-乳头肌连续性的重要性。
我们研究了21例行二尖瓣置换术的患者,随机分为两组:第1组,12例患者行二尖瓣置换术,保留后叶及相应腱索;第2组,9例患者行传统二尖瓣置换术,切除二尖瓣装置。术前和术后均通过超声心动图、心导管检查和放射性同位素研究对左心室功能进行研究。采用威尔科克森检验进行统计分析。
术后早期无死亡病例。通过放射性同位素研究分析射血分数结果,我们发现两组百分比下降之间存在显著差异(p = 0.03)。第1组的缩短分数结果高于第2组,但无统计学意义。第1组的左心室舒张直径平均值低于第2组,左心房直径也是如此。通过心导管检查,我们发现第1组左心室舒张末期压力降低,而第2组升高。第1组肺动脉和肺毛细血管压力均成比例增加。右心室舒张末期压力平均值之间存在显著差异(p = 0.05)。
第1组左心室功能保留得更好。