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[外周血淋巴细胞中的胆固醇水平:不同类型高脂血症患者与缺血性心脏病的相互关系]

[The cholesterol level in the peripheral blood lymphocytes: the interrelationship with ischemic heart disease in patients with different types of hyperlipidemia].

作者信息

Bolkhova L A, Fuki I V, Solov'eva E Iu, Koshechkin V A, Repin V S

出版信息

Biull Eksp Biol Med. 1993 Nov;116(11):476-9.

PMID:8312533
Abstract

Variability of cholesterol levels inside lymphocytes (CLL) have been compared with the concentration of total cholesterol, triglycerides and HDL of blood plasma among normal donors and hyperlipidemic patients. Persons with elevated CLL was found among normal donors and hyperlipidemic patients, each group comprising 4-5%. No significant correlation was followed between CLL & the level of total cholesterol, triglyceride & HDL blood plasma level among total observed population. However a consistent correlation was found between CLL & blood plasma cholesterol/triglyceride ratio among patient with elevated plasma triglyceride.

摘要

已将淋巴细胞内胆固醇水平(CLL)的变异性与正常供体和高脂血症患者血浆中总胆固醇、甘油三酯和高密度脂蛋白的浓度进行了比较。在正常供体和高脂血症患者中均发现了CLL升高的个体,每组占4 - 5%。在所有观察人群中,CLL与总胆固醇水平、甘油三酯及血浆高密度脂蛋白水平之间未发现显著相关性。然而,在血浆甘油三酯升高的患者中,发现CLL与血浆胆固醇/甘油三酯比值之间存在一致的相关性。

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