噬菌体T7 RNA聚合酶的结构与功能（或者说，简单性的优点）
Structure and function of the bacteriophage T7 RNA polymerase (or, the virtues of simplicity).
作者信息
McAllister W T
机构信息
Department of Microbiology and Immunology, Morse Institute of Molecular Genetics, SUNY Health Science Center, Brooklyn 11203-2098.
出版信息
Cell Mol Biol Res. 1993;39(4):385-91.
PMID:8312975
Abstract
A consideration of the properties of a number of mutants of T7 RNA polymerase, together with emerging structural information (Sousa et al., 1993) allows an interpretation of the the mechanics of transcription by this relatively simple RNA polymerase. Evidence indicating features in common with other nucleotide polymerases (such as DNA polymerases and reverse transcriptases) is reviewed.
摘要
对T7 RNA聚合酶多个突变体的特性进行研究，并结合新出现的结构信息（苏萨等人，1993年），有助于解释这种相对简单的RNA聚合酶的转录机制。本文综述了表明其与其他核苷酸聚合酶（如DNA聚合酶和逆转录酶）具有共同特征的证据。
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