Deng G H
Peking Union Medical College Hospital, Beijing.
Zhonghua Yi Xue Za Zhi. 1993 Oct;73(10):599-601, 637.
Thirty-six cases of pseudomonas aeruginosa septicemia were found in 5 years from 1986 to 1990. The main risk factors predisposing septicemia included severe underlying diseases and local primary infection or impaired anatomic barrier. The use of broad-spectrum antibiotics, cytotoxic or immunosuppressive therapy, and leukopenia were also important risk factors. The percentages of in vitro resistant strains to 8 antipseudomonal antibiotics varied from 18% to 47%. The overall effective rate was 42% in 26 patients receiving appropriate antibiotic therapy. The mortality attributable to pseudomonas aeruginosa septicemia was 61%. The prevention and antibiotic treatment of pseudomonas aeruginosa septicemia are discussed.
1986年至1990年的5年间共发现36例铜绿假单胞菌败血症。引发败血症的主要危险因素包括严重的基础疾病、局部原发性感染或解剖屏障受损。使用广谱抗生素、细胞毒性或免疫抑制疗法以及白细胞减少也是重要的危险因素。体外对8种抗假单胞菌抗生素耐药菌株的百分比在18%至47%之间。26例接受适当抗生素治疗的患者总体有效率为42%。铜绿假单胞菌败血症所致死亡率为61%。本文讨论了铜绿假单胞菌败血症的预防和抗生素治疗。
