[Immunomorphological study of the liver in clinical and experimental postnecrotic cirrhosis].

Immunomorphological study of the liver was carried out in 5 dead patients with postnecrotic cirrhosis of the liver and in 50 white rats with experimental cirrhosis of the liver for the purpose of detection of fixed immunoglobulins localization. Saturation with gamma-globulins of the vessel walls, forming connective-tissue septae and hepatocytes undergoing degeneration was established in rats. In man, gamma-globulins were found in the connective tissue strands, in vessel walls, and in the cytoplasm of mesenchymal cells and hepatocytes. The analysis of the results suggests different origin and dissimilar importance of gamma-globulins in different structures of the liver.