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[宫颈癌体外及腔内后装放射治疗:110例报告]

[External and intracavitary afterloading radiotherapy of cervical cancer: a report of 110 cases].

作者信息

Jiang Z X

机构信息

Hubei Cancer Hospital, Wuhan.

出版信息

Zhonghua Fu Chan Ke Za Zhi. 1993 Nov;28(11):651-2, 699-700.

PMID:8313730
Abstract

Radiation therapy is one of the major methods among the multidisciplinary treatments for carcinoma of the uterine cervix. A series of 110 patients with carcinoma of uterine cervix treated from May 1987 to December 1987 by 3-channel (Cs-137) Buchler afterloading was presented. The youngest patients was 31 while the oldest was 78 years old with an average age of 56 years. Squamous cell carcinoma was found in 104 of the patients, while 6 had adenocarcinomas. There were 2 cases with Stage I, 17 Stage II and 91 Stage III lesions. Whole pelvis irradiation was delivered with two large parallel anterior-posterior opposite fields. The dose was 2.5-3Gy given in one field a day, three times a week, the total dose was 42-52Gy at the middle line plane of pelvis. Intracavitary irradiation was started a week following the external irradiation. The dose rate at point A was 0.1-0.26Gy/min. The project was designed to deliver 25-30 Gy to point A by 5-6 frequency. The over-all 5-year survival rate of the whole series was 70%, with 82% for Stage II and 67% for Stage III lesions. The frequency of late rectal and bladder reactions was 10.9% and 4.5%, respectively.

摘要

放射治疗是子宫颈癌多学科治疗中的主要方法之一。本文报告了1987年5月至1987年12月期间采用三通道(铯-137)布赫勒后装治疗的110例子宫颈癌患者。最年轻的患者31岁,最年长的78岁,平均年龄56岁。104例患者为鳞状细胞癌,6例为腺癌。I期病变2例,II期17例,III期91例。采用两个大的前后对穿平行野进行全盆腔照射。剂量为每天一个野给予2.5 - 3Gy,每周三次,在盆腔中线平面的总剂量为42 - 52Gy。腔内照射在体外照射一周后开始。A点剂量率为0.1 - 0.26Gy/分钟。该方案设计为通过5 - 6次照射使A点剂量达到25 - 30Gy。全组总的5年生存率为70%,II期病变为82%,III期病变为67%。晚期直肠和膀胱反应的发生率分别为10.9%和4.5%。

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