Williams A J, Ireland J T
Acta Paediatr Scand. 1977 Jan;66(1):117-9. doi: 10.1111/j.1651-2227.1977.tb07817.x.
Investigation of a neonate presenting with a metabolic acidosis, vomiting and an apnoeic attack revealed abnormal urinary excretion of methylmalonic acid (MMA) associated with a low serum vitamin B12. Restriction of dietary protein was followed by normalisation of acid-base balance. Reintroduction of normal daily protein intake did not precipitate flrther acidosis or increased excretion of MMA. The transient methylmalonicaciduria was probably due to deficiency of vitamin B12.
对一名出现代谢性酸中毒、呕吐和呼吸暂停发作的新生儿进行检查发现，其尿中甲基丙二酸（MMA）排泄异常，同时血清维生素B12水平较低。限制饮食中的蛋白质摄入后，酸碱平衡恢复正常。重新恢复正常的每日蛋白质摄入量并未引发进一步的酸中毒或MMA排泄增加。这种短暂性甲基丙二酸尿症可能是由于维生素B12缺乏所致。
