Zidi S H, Marteau P, Piard F, Coffin B, Favre J P, Rambaud J C
Service de Gastro-entérologie, Hôpital Saint-Lazare, Paris, France.
Dig Dis Sci. 1994 Feb;39(2):426-32. doi: 10.1007/BF02090219.
Enteritis cystica profunda and diffuse colitis cystica profunda are exceedingly rare conditions. We report here the first case in which these two entities are associated in one patient. This 48-year-old woman presented initially with a solitary ulcer of the rectum and developed later deep ileal and colonic ulcerations with intervening normal mucosa, polypoid masses, and a dense fibrosis of the bowel wall. Colon and ileum specimens demonstrated submucosal mucous cysts and occasionally herniation of mucosal epithelium into the submucosa, which led to the diagnosis of enteritis and colitis cystica profunda. The exact nature of the underlying ileocolonic disease, which necessitated colectomy and extensive ileal resection, remained undetermined although an aggravating role of iterative surgical procedures is possible. Enteritis cystica profunda and diffuse colitis cystica profunda therefore seem to share a common pathogeny and have to be considered as lesions complicating an underlying disease rather than specific and autonomic diseases.
深部囊性肠炎和弥漫性深部囊性结肠炎是极为罕见的病症。我们在此报告首例这两种病变在同一患者中并存的病例。这位48岁女性最初表现为直肠单发溃疡，随后出现深部回肠和结肠溃疡，其间有正常黏膜、息肉样肿物以及肠壁致密纤维化。结肠和回肠标本显示黏膜下黏液囊肿，偶尔可见黏膜上皮疝入黏膜下层，据此诊断为深部囊性肠炎和深部囊性结肠炎。尽管反复手术操作可能起加重作用，但导致必须行结肠切除术和广泛回肠切除术的潜在回结肠疾病的确切性质仍未明确。因此，深部囊性肠炎和弥漫性深部囊性结肠炎似乎具有共同的发病机制，应被视为潜在疾病的并发症，而非特异性自主疾病。
