基因研究中的脂蛋白亚类：伯克利数据集

Lipoprotein subclasses in genetic studies: the Berkeley data set.

作者信息

Krauss R M, Williams P T, Blanche P J, Cavanaugh A, Holl L G, Austin M A

机构信息

Life Sciences Division, Lawrence Berkeley Laboratory, University of California, Berkeley.

出版信息

Genet Epidemiol. 1993;10(6):523-8. doi: 10.1002/gepi.1370100632.

DOI:10.1002/gepi.1370100632

PMID:8314054

Abstract

In conjunction with a study examining the inheritance of LDL subclass patterns in a healthy population, measurements of lipids, lipoproteins, and lipoprotein subclasses were performed in 301 individuals in 27 kindreds. Questionnaires were used to obtain information on use of medications, hormones, cigarettes, and alcohol. Laboratory data from this study (the Berkeley data set) include measurements of LDL and HDL size subclasses by nondenaturing gradient gel electrophoresis, and measurement of apolipoprotein A-I by radial immunodiffusion.

摘要

在一项关于健康人群低密度脂蛋白亚类模式遗传的研究中，对27个家族的301名个体进行了脂质、脂蛋白和脂蛋白亚类的测量。通过问卷调查获取了用药、激素、吸烟和饮酒方面的信息。该研究（伯克利数据集）的实验室数据包括通过非变性梯度凝胶电泳测量低密度脂蛋白和高密度脂蛋白大小亚类，以及通过放射免疫扩散测量载脂蛋白A-I。