Brumana N, Scheidler D, Bonato M, Zingaro R, Salmini G
Divisione di Medicina Generale C, Ospedale di Circolo di Varese.
Haematologica. 1993 Sep-Oct;78(5):335-7.
We report on a 63-year-old febrile woman who was diagnosed as having Hodgkin's disease (HD), after laparotomy. About one and half years later, while on a second line therapy for HD, the patient developed superficial diffuse adenomegaly. At that time, an M component was detected in the serum; bone marrow aspirate and biopsy were consistent with multiple myeloma (MM). An axillary lymphnode biopsy was performed and revealed a peripheral T cell lymphoma (PTCL). On reviewing previous samples the earlier diagnosis of HD was rejected and a diagnosis of PTCL was postulated. The clinical course of the patient was rapidly down-hill; she died soon after hospital admission.
我们报告了一名63岁发热女性，剖腹手术后被诊断为霍奇金淋巴瘤（HD）。大约一年半后，在接受HD二线治疗时，患者出现浅表弥漫性淋巴结肿大。当时，血清中检测到M蛋白成分；骨髓穿刺和活检结果符合多发性骨髓瘤（MM）。进行了腋窝淋巴结活检，结果显示为外周T细胞淋巴瘤（PTCL）。回顾之前的样本后，早期HD诊断被否定，推测诊断为PTCL。患者临床病程迅速恶化；入院后不久死亡。
