The CD8 alpha locus is located on the telomere side of the immunoglobulin kappa locus at a distance of 2 Mb.
作者信息
Weichhold G M, Huber C, Parnes J R, Zachau H G
机构信息
Institut für Physiologische Chemie, Universität München, Germany.
出版信息
Genomics. 1993 May;16(2):512-4. doi: 10.1006/geno.1993.1218.
PMID:8314589
Abstract
The immunoglobulin kappa and CD8 alpha loci had been mapped by in situ hybridization to the short arm of chromosome 2 at 2cen-p11.2 and 2p1, respectively, but probes derived from the two loci did not hybridize to the same large PFGE fragments. We have now succeeded in linking the two loci on a 3.0-Mb fragment from a partial NruI digest. A new hybridization probe located between the two loci provided additional linking fragments and allowed the distance to be determined as 2.0-2.2 Mb.
摘要
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