Sautter F, McDermott B, Garver D
Tulane University School of Medicine.
J Clin Psychol. 1993 May;49(3):339-44. doi: 10.1002/1097-4679(199305)49:3<339::aid-jclp2270490306>3.0.co;2-q.
This study compared the course of illness of 36 patients who received a diagnosis of either DSM-III-R schizophreniform disorder or schizophrenia. Approximately 3.5 and 4.0 years after their index hospitalization, the two groups were compared for differences in positive and negative symptoms of psychosis, interpersonal and occupational role functioning, and other aspects of the deficit state. Multivariate data analyses indicate that the course of illness of the two groups is significantly different (p < .007), and the data also indicate that patient symptoms and functioning changed significantly over time (p < .008). The schizophreniform patients showed a low level of negative symptoms at both follow-ups; schizophrenics initially showed a higher level of negative symptoms, but these symptoms decreased significantly over time (p < .04). These data indicate that the course of DSM-III-R schizophreniform disorder is distinct from the course of schizophrenia.
本研究比较了36名被诊断为DSM-III-R精神分裂症样障碍或精神分裂症患者的病程。在他们首次住院约3.5年和4.0年后，比较两组在精神病性的阳性和阴性症状、人际及职业角色功能以及缺陷状态的其他方面的差异。多变量数据分析表明，两组的病程有显著差异（p < .007），数据还表明患者的症状和功能随时间有显著变化（p < .008）。精神分裂症样障碍患者在两次随访时阴性症状水平都较低；精神分裂症患者最初阴性症状水平较高，但这些症状随时间显著减少（p < .04）。这些数据表明，DSM-III-R精神分裂症样障碍的病程与精神分裂症的病程不同。
